Publications

All Data Sources Primary Data Collection Secondary Data Sources Evidence synthesis
All Topics Menopause Endometriosis Oncology Dermatology Cardiovascular Disease Diabetes Other Contraception
Showing 1–30 of 256 publications
2026
Patient Burden in the Treatment of Wilson Disease in the United States: An Analysis of Real-World Health Insurance Claims Data from the Komodo database Hedera Peter, Teynor Megan, Strader Carey, Costantino Halley, Michael Schultze, Akumo Divine, Weiss Karl Heinz 2026 Advances in Therapy → DOI
Other
Polished but pointless? Assessing the potential of gold and silver-alloy IUDs versus copper-only devices in a large multinational cohort (EURAS- LCS12)  Boehnke Tanja, Lisa Eggebrecht, Rizzo Manuel, Klinghardt Moritz, Klaas Heinemann 2026 Contraception & Reproductive Health Care → DOI
Contraception
2025
Real-world psoriasis treatment patterns and disease burden in Germany, with a focus on biologics and apremilast: data from a German statutory health insurance database Pinter Andreas, Schulte Marcus, Kossack Nils, Marc Pignot, Michael Schultze, Feldhus Andrea 2025 JME: Journal of Medical Economics. 2025; VOL. 28, NO. 1, 207-220. 10.1080/13696998.2025.2452054. → DOI
Dermatology
Real-world treatment patterns and survival outcomes in patients with locally advanced squamous cell carcinoma of the head and neck in Germany using claims data Hering Kathrin, Kuhnt Thomas, Kossack Nils, Richter Lena M., Michael Schultze, Osowski Ulrike, Henkel Luisa, Gaupel Ann-Christin, Solbes Marie-Noelle, Zolyniak Bernard, Schoenherr Nancy 2025 Front. Oncol. 2025; Vol. 15:1547311. 10.3389/fonc.2025.1547311. → DOI
Oncology
Real-world use of antispasmodic drugs during IUD insertion – insights from the large observational study EURAS-LCS12 Lisa Eggebrecht, Rizzo Manuel, Klinghardt Moritz, Boehnke Tanja, Clare Barnett, Klaas Heinemann 2025 Contraception & Reproductive Health Care . 2025; 10.1080/13625187.2025.2480086. → DOI
Contraception
Real-world validation of a bleeding prediction algorithm in levonorgestrel intrauterine device users using the MyIUS mobile app Sales Vieira Carolina, Lisa Eggebrecht, Milhoranca Igor Andre, Neumann Robert, Schiffer Acar Mariana, von Stockum Sophia, Frenz Ann-Kathrin 2025 Contraception. 2025; 10.1016/j.contraception.2025.111201. → DOI
Contraception
Risk of venous thromboembolism associated with chlormadinone acetate- and levonorgestrel-containing combined oral contraceptives – Insights from the retrospective RIVET-RCS study Pauline De Corte, Klinghardt Moritz, Bauerfeind Anja, Boehnke Tanja, Klaas Heinemann 2025 Contraception. 2025; 10.1016/j.contraception.2025.111251. → DOI
Contraception
Use of oral medications prior to IUD insertion – Trends and associations of patient characteristics in a large observational study in Europe (EURAS-LCS12) Klinghardt Moritz, Rizzo Manuel, Boehnke Tanja, Clare Barnett, Klaas Heinemann, Lisa Eggebrecht 2025 Eur J Obstet Gynecol Reprod Biol.. 2025; 10.1016/j.ejogrb.2025.114789. → DOI
Contraception
A Real-World Evaluation of Brain Imaging in Patients with Advanced Non-Small Cell Lung Cancer: Insights from a German Claims Data Analysis Atmaca Akin, Grohé Christian, Klinghardt Moritz, Kossack Nils, Marc Pignot, Schuh Roxana 2025 Oncol Res Treat. 2025; 10.1159/000547215. → DOI
Oncology
Endometriosis and risk of depression among oral contraceptive users: a pooled analysis of cohort studies from 13 countries Pauline De Corte, Milhoranca Igor Andre, Oberg Anna Sara, Kurth Tobias, Mechsner Sylvia, Klaas Heinemann 2025 Human Reproduction. 2025; 1-8. 10.1093/humrep/deae299. → DOI
Endometriosis
Epidemiology and burden of mild/moderate versus high myopia in Germany: A claims data analysis. Tarcyane Barata Garcia, Kossack Nils, Marc Pignot, Mohammed Dagher, Schuster Alexander K., Wielink Kun Shi-van 2025 Acta Ophthalmologica. 2025; 10.1111/aos.17589.
Dermatology
Epidemiology of generalized pustular psoriasis in Germany: Analyzing factors influencing prevalence estimates from claims data. Michael Schultze, Kossack Nils, Kromer Christian, Zimmermann Thomas M., Nikolaus Kolb 2025 JDDG: J Dtsch Dermatol Ges.. 2025; 10.1111/ddg.15633. → DOI
Dermatology
Population characteristics of intrauterine device users in real-world clinical practice across Europe – insights from the EURAS-LCS12 study Lisa Eggebrecht, Bauerfeind Anja, Boehnke Tanja, Rizzo Manuel, Hagemann Christine, Jens A. Lange, Viet Mareike, Karl Pauls, von Stockum Sophia, Klinghardt Moritz, Klaas Heinemann 2025 Contraception and Reproductive Medicine. 2025; 10.1186/s40834-025-00353-8. → DOI
Contraception
2024
Time to Diagnose Endometriosis: Current Status, Challenges and Regional Characteristics – A Systematic Literature Review Pauline De Corte, Klinghardt Moritz, von Stockum Sophia, Klaas Heinemann 2024 BJOG: An International Journal of Obstetrics & Gynaecology. 2024; 1-13. 10.1111/1471-0528.17973. → DOI
Endometriosis
Unravelling the Causal Relationship between Endometriosis and the Risk for Developing Venous Thromboembolism: A Pooled Analysis Pauline De Corte, Milhoranca Igor Andre, Mechsner Sylvia, Oberg Anna Sara, Kurth Tobias, Klaas Heinemann 2024 Thrombosis and Haemostasis. 2024; 10.1055/a-2407-9498. → DOI
Endometriosis
Unveiling the untreated: development of a database algorithm to identify potential Fabry disease patients in Germany Hilz M., Lyn N, Marczykowski F., Werner B., Marc Pignot, Ponce E, Bender J., Edigkaufer M., Das Mahapatra P. 2024 Orphanet J Rare Dis. 2024; 10.1186/s13023-024-03258-y. → DOI
Other
Venous Thromboembolic Risk of Estradiol Valerate–Dienogest Compared with Ethinyl Estradiol–Levonorgestrel Combined Oral Contraceptives. Bauerfeind Anja, von Stockum Sophia, Boehnke Tanja, Klaas Heinemann 2024 Obstetrics & Gynecology. 2024; 10.1097/AOG.0000000000005509. → DOI
Contraception
[Clinical courses and costs for hospitalizations of potentially immunocompromised COVID-19 patients in Germany] Häckl Dennis, Marc Pignot, Long Dang Phi, Lauenroth Victoria, Jah Fungwe, Wendtner Clemens-Martin 2024 Dtsch Med Wochenschr. 2024; e38-e46. 10.1055/a-2239-0453. → DOI
Other
Does the shape of the copper intrauterine device play a role in expulsion? Results from the ongoing European Active Surveillance Study on LCS12 Boehnke Tanja, Bauerfeind Anja, Lisa Eggebrecht, Cellier Camille, Jens A. Lange, Klaas Heinemann, Madden Tessa 2024 Contraception. 2024; https://doi.org/10.1016/j.contraception.2024.110444. → DOI
Contraception
Effectiveness of the etonogestrel subdermal implant in users with overweight and obesity: a systematic literature review Goto Daisuke, Grunden John W, Klinghardt Moritz, Perez Patel Vanessa, von Stockum Sophia, Clare Barnett, Bitzer Johannes 2024 BMJ Sexual & Reproductive Health. 2024; 0.1136/bmjsrh-2024-202424. → DOI
Contraception
Epidemiology of Wilson disease in Germany – real-world insights from a claims data study Fang Shona, Hedera Peter, Borchert Julia, Michael Schultze, Weiss Karl Heinz 2024 Orphanet J Rare Dis. 2024; 10.1186/s13023-024-03351-2. → DOI
Other
Impact of progestin type on the risk of drug interactions between combined oral contraceptives and psychotropic drugs: A pooled analysis of real-world data Boehnke Tanja, Franke Christian, Bauerfeind Anja, Klaas Heinemann, Kolberg-Liedtke Cornelia, Koelkebeck Katja 2024 Contraception. 2024; 10.1016/j.contraception.2024.110786. → DOI
Contraception
The Impact of Systemic Lupus Erythematosus Flares on Clinical and Economic Outcomes: The CHAMOMILE Claims Database Study in Germany Ding Bo, Marc Pignot, Garal-Pantaler Elena, Villinger Beate, Schefzyk Sebastian, Desta Barnabas, Stirnadel-Farrant Heide, Schwarting Andreas 2024 Rheumatol Ther. 2024; 10.1007/s40744-023-00635-0. → DOI
Other
2023
Comorbidities, healthcare resource utilization & treatment pattern among patients with prurigo nodularis, compared to a benchmark in Germany: A real-world evidence claims data study Ständer Sonja, Ketz Miriam, Akumo Divine, Kossack Nils, Marc Pignot, Chavda Rajeev, Gabriel Sylvie 2023 J Eur Acad Dermatol Venerol. 2023; 1-12. 10.1111/jdv.19700. → DOI
Dermatology
How did regional lockdowns during the COVID-19 pandemic affect recruitment into a large multinational cohort study of intrauterine device users? Boehnke Tanja, Lisa Eggebrecht, Viet Mareike, Klaas Heinemann, Bauerfeind Anja 2023 Contraception. 2023; 10.1016/j.contraception.2023.110003. → DOI
Contraception
2022
Corticosteroid Use in Patients With Systemic Lupus Erythematosus in Germany: The CHAMOMILE Claims Database Study. 2022 DGRh 2022, Berlin, Germany 31 August–3 September. 2022;
Cardiovascular Disease
Disease Burden, Healthcare Resource Utilization & Treatment Pattern among Patients with Prurigo Nodularis compared to a Benchmark in Germany: A Real-World-Evidence Claims Data Study. 2022 31st EADV Congress, Milan. 2022;
Dermatology
Intrauterine device prescribing patterns and types in Europe – a cross-sectional analysis of the European Active Surveillance LCS12 Study. 2022 European Gynecology & Obstetrics. 2022; 29–40. 10.53260/EGO.224015 .
Contraception
Long-term real-world effectiveness of allergy immunotherpay in patients with allergic rhinitis and asthma: Results from the REACT study, a retrospective cohort study Fritzsching Benedikt, Contoli Marco, Porsbjerg Celeste, Buchs Sarah, Rask Larsen Julie, Elliott Lisa, Romano Rogdriguez Mercedes, Freemantle Nick 2022 The Lancet Regional Health Volume 13. 2022; → DOI
Other
Population estimates of obstructive and non-obstructive hypertrophic cardiomyopathy in the UK and Germany. 2022 2022;
Cardiovascular Disease
All years 2025 2024 2023
All types Real-World Evidence Prospective Cohort Secondary Data Review Meta-analysis Methodology Case-Control
2025
Use of oral medications prior to IUD insertion – Trends and associations of patient characteristics in a large observational study in Europe (EURAS-LCS12)
Prospective Cohort
Klinghardt M, Rizzo M, Boehnke T, Barnett C, Heinemann K, Eggebrecht L
2025 Eur J Obstet Gynecol Reprod Biol → DOI
A Real-World Evaluation of Brain Imaging in Patients with Advanced Non-Small Cell Lung Cancer: Insights from a German Claims Data Analysis
Secondary Data
Atmaca A, Grohé C, Klinghardt M, Kossack N, Pignot M, Schuh R
2025 Oncol Res Treat → DOI
Endometriosis and risk of depression among oral contraceptive users: a pooled analysis of cohort studies from 13 countries
Meta-analysis
De Corte P, Milhoranca IA, Oberg AS, Kurth T, Mechsner S, Heinemann K
2025 Human Reproduction → DOI
Epidemiology and burden of mild/moderate versus high myopia in Germany: A claims data analysis
Secondary Data
Barata Garcia T, Kossack N, Pignot M, Dagher M, Schuster AK, Wielink KS
2025 Acta Ophthalmologica → DOI
Epidemiology of generalized pustular psoriasis in Germany: Analyzing factors influencing prevalence estimates from claims data
Secondary Data
Schultze M, Kossack N, Kromer C, Zimmermann TM, Kolb N
2025 JDDG → DOI
Population characteristics of intrauterine device users in real-world clinical practice across Europe – insights from the EURAS-LCS12 study
Real-World Evidence
Eggebrecht L, Bauerfeind A, Boehnke T, Rizzo M, Lange JA, Heinemann K et al.
2025 Contraception and Reproductive Medicine → DOI
Real-world psoriasis treatment patterns and disease burden in Germany, with a focus on biologics and apremilast
Real-World Evidence
Pinter A, Schulte M, Kossack N, Pignot M, Schultze M, Feldhus A
2025 Journal of Medical Economics → DOI
Real-world use of antispasmodic drugs during IUD insertion – insights from the large observational study EURAS-LCS12
Real-World Evidence
Eggebrecht L, Rizzo M, Klinghardt M, Boehnke T, Barnett C, Heinemann K
2025 Contraception & Reproductive Health Care → DOI
Risk of venous thromboembolism associated with chlormadinone acetate- and levonorgestrel-containing combined oral contraceptives – RIVET-RCS study
Case-Control
De Corte P, Klinghardt M, Bauerfeind A, Boehnke T, Heinemann K
2025 Contraception → DOI
2024
Does the shape of the copper intrauterine device play a role in expulsion? Results from the ongoing European Active Surveillance Study on LCS12
Prospective Cohort
Boehnke T, Bauerfeind A, Eggebrecht L, Cellier C, Lange JA, Heinemann K, Madden T
2024 Contraception → DOI
Effectiveness of the etonogestrel subdermal implant in users with overweight and obesity: a systematic literature review
Review
Goto D, Grunden JW, Klinghardt M, Perez Patel V, Barnett C, Bitzer J
2024 BMJ Sexual & Reproductive Health → DOI
Epidemiology of Wilson disease in Germany – real-world insights from a claims data study
Secondary Data
Fang S, Hedera P, Borchert J, Schultze M, Weiss KH
2024 Orphanet J Rare Dis → DOI
Impact of progestin type on the risk of drug interactions between combined oral contraceptives and psychotropic drugs: A pooled analysis of real-world data
Real-World Evidence
Boehnke T, Franke C, Bauerfeind A, Heinemann K, Kolberg-Liedtke C, Koelkebeck K
2024 Contraception → DOI
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